{"id":670,"date":"2025-07-21T10:34:28","date_gmt":"2025-07-21T14:34:28","guid":{"rendered":"https:\/\/fondationduchum.com\/?p=670"},"modified":"2026-02-12T10:34:28","modified_gmt":"2026-02-12T15:34:28","slug":"envisioning-personalized-treatment-for-patients-living-with-epilepsy","status":"publish","type":"post","link":"https:\/\/fondationduchum.com\/en\/news\/envisioning-personalized-treatment-for-patients-living-with-epilepsy\/","title":{"rendered":"Envisioning personalized treatment for patients living with epilepsy"},"content":{"rendered":"\n<p><em>Find out how donations are making CHUM teams\u2019 inspiring ideas a reality.<\/em><\/p>\n\n\n\n<p>Imagine if doctors could make a personalized <strong>\u201cgenetic avatar\u201d<\/strong> for every epilepsy patient and use it to identify the most effective treatment for that individual. This innovative approach could change countless lives\u2014and thanks to donation-supported research led by Dr. \u00c9ric Samarut, researcher at the CHUM Research Centre (CRCHUM), it may become a reality.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Acting faster than epilepsy with precision medicine<\/h2>\n\n\n\n<div class=\"wp-block-media-text is-stacked-on-mobile\"><figure class=\"wp-block-media-text__media\"><img decoding=\"async\" width=\"540\" height=\"405\" src=\"https:\/\/fondationduchum.com\/wp-content\/uploads\/2025\/10\/Samarut_-Eric-4916m-e1753107528537.jpg\" alt=\"\" class=\"wp-image-485 size-full\" srcset=\"https:\/\/fondationduchum.com\/wp-content\/uploads\/2025\/10\/Samarut_-Eric-4916m-e1753107528537.jpg 540w, https:\/\/fondationduchum.com\/wp-content\/uploads\/2025\/10\/Samarut_-Eric-4916m-e1753107528537-300x225.jpg 300w\" sizes=\"(max-width: 540px) 100vw, 540px\" \/><\/figure><div class=\"wp-block-media-text__content\">\n<p>Today, epilepsy treatments are too often chosen through trial and error. This is a long, unpredictable process that can have irreversible effects on patients\u2019 health and compromise the future effectiveness of their medication. <\/p>\n\n\n\n<p>Nearly a third of the 350,000 patients living with epilepsy in Canada do not respond well to existing medications. Their quality of life is lowered, as they continue to experience seizures. <\/p>\n\n\n\n<p>CRCHUM\u2019s scientists are tackling the issue by using the latest developments in genomics and precision medicine to respond faster, more effectively and in a more personalized way to each patient as soon as their treatment begins.<\/p>\n<\/div><\/div>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<p><em>\u201cThanks to these donations, we\u2019re developing technology that will help us give every patient treatment based on their own genetics. Philanthropy gives us the freedom to explore new ideas and turn them into real solutions for everyone.\u201d <\/em><\/p>\n\n\n\n<p><strong>Dr. \u00c9ric Samarut<\/strong><\/p>\n<\/blockquote>\n\n\n\n<h2 class=\"wp-block-heading\">A key step toward creating personalized genetic avatars<\/h2>\n\n\n\n<div class=\"wp-block-media-text is-stacked-on-mobile\"><figure class=\"wp-block-media-text__media\"><img decoding=\"async\" width=\"640\" height=\"416\" src=\"https:\/\/fondationduchum.com\/wp-content\/uploads\/2025\/10\/equipe-Eric-Samarut-4910m.jpeg\" alt=\"Equipe-docteur-samarut\" class=\"wp-image-671 size-full\" srcset=\"https:\/\/fondationduchum.com\/wp-content\/uploads\/2025\/10\/equipe-Eric-Samarut-4910m.jpeg 640w, https:\/\/fondationduchum.com\/wp-content\/uploads\/2025\/10\/equipe-Eric-Samarut-4910m-300x195.jpeg 300w\" sizes=\"(max-width: 640px) 100vw, 640px\" \/><\/figure><div class=\"wp-block-media-text__content\">\n<p>The teams developed several specific lines of zebrafish\u2014a valuable model for biomedical research. These lines replicate the genetic mutations responsible for epilepsy and the treatment responses observed in patients, allowing researchers to test out the best treatment for each individual. <\/p>\n\n\n\n<p>This precision medicine research initiative and the creation of personalized genetic avatars promise to revolutionize the care experience for epilepsy patients, both at the CHUM and around the world. <\/p>\n\n\n\n<p><strong>Thanks to our generous donors, philanthropy is driving the future of medicine and building a more compassionate, precise and effective healthcare system, here at the CHUM.<\/strong><\/p>\n<\/div><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Find out how donations are making CHUM teams\u2019 inspiring ideas a reality. Imagine if doctors[&#8230;];<\/p>\n","protected":false},"author":1,"featured_media":671,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[19],"tags":[],"class_list":["post-670","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-impacts-and-achievements"],"acf":[],"_links":{"self":[{"href":"https:\/\/fondationduchum.com\/en\/wp-json\/wp\/v2\/posts\/670","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/fondationduchum.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/fondationduchum.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/fondationduchum.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/fondationduchum.com\/en\/wp-json\/wp\/v2\/comments?post=670"}],"version-history":[{"count":2,"href":"https:\/\/fondationduchum.com\/en\/wp-json\/wp\/v2\/posts\/670\/revisions"}],"predecessor-version":[{"id":677,"href":"https:\/\/fondationduchum.com\/en\/wp-json\/wp\/v2\/posts\/670\/revisions\/677"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/fondationduchum.com\/en\/wp-json\/wp\/v2\/media\/671"}],"wp:attachment":[{"href":"https:\/\/fondationduchum.com\/en\/wp-json\/wp\/v2\/media?parent=670"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/fondationduchum.com\/en\/wp-json\/wp\/v2\/categories?post=670"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/fondationduchum.com\/en\/wp-json\/wp\/v2\/tags?post=670"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}